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Biologic Basis of Ovarian Cancer

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Ovarian cancer is characterized by complex cellular and molecular processes.

It is both histologically and molecularly heterogeneous:

  • Histological subtypes impact prognosis

  • The identification of molecular aberrations, such as BRCA1/2 mutations and homologous recombination repair pathway deficiencies have shaped treatment strategies

The tumor microenvironment affects the disease process and potentially clinical outcomes.

Explore the module further to learn more about the biologic basis of ovarian cancer—or download the module for later review offline.

Understanding the biology of ovarian cancer is important for appropriate clinical management of the disease.

MICHAEL J. BIRRER, MD, PhD
The University of Alabama at Birmingham
GEMSTONE Committee Chair: Michael J. Birrer, MD, PhD
GEMSTONE Oncology infographic ‐ ovarian cancer is characterized by complex cellular and molecular processes

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